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Symptoms of Metabolic Syndrome (Syndrome X)


Metabolic Syndrome has Many SymptomsMetabolic Syndrome causes heart disease and increases the risk of a heart attack or stroke. But many people of both sexes are unaware that they are suffering from this disorder, even though the American Heart Association estimates that 20-25% of the adult population of the U.S. has the condition.

That means between 58 and 73 million men and women are at risk from a disorder that can cause major damage to the cardiovascular system. Combating this condition is a key factor in heart disease prevention.

Metabolic Syndrome is characterized by having at least three of the following symptoms:

  • Insulin Resistance (when the body can’t absorb blood sugar or utilize insulin properly)
  • Abdominal fat – in men this means a 40 inch waist or larger, in women 35 inches or larger
  • High blood sugar levels – at least 110 milligrams per deciliter (mg/dL) after fasting
  • High triglycerides – at least 150 mg/dL in the blood stream
  • Low HDL (the “good” cholesterol) – less than 40 mg/dL if male and 50 mg/dL if female
  • Prothrombotic state (e.g. high fibrinogen or plasminogen activator inhibitor in the blood)
  • Blood pressure of 130/85 mmHg or higher

The American Heart Association states that the “underlying causes of Metabolic Syndrome are being overweight, physical inactivity and genetic factors.”

Crucial developments in Metabolic Syndrome are weight gain and obesity, which can be caused by Insulin Resistance. This latter disorder prevents the efficient conversion of food, or glucose, into energy via the cells walls have become desensitized to insulin by Insulin Resistance.

Metabolic Syndrome has Many SymptomsAs a result, glucose floats freely in the blood stream, causing elevated levels of blood sugar, which are sent to the liver. Once there, the sugar is converted into fat and circulated via the blood stream throughout the body in a process that can lead to weight gain and obesity. Insulin Resistance can severly impair your ability to lose weight.

Free-floating insulin, as a result of Insulin Resistance, also has a harmful affect. It can damage the lining of the arteries and contribute to the development of atherosclerosis, which is characterized by a dangerous build-up of plaque on the artery walls.

“As a new insulin guy who has gone through the nightmare of adjusting doses and known Insulin Resistance as a horrible lack of knowledge on the subject, you gave me some hope for the future. Thanks."
K.A.
  North Olmsted, OH
In addition, the imbalance of glucose and insulin can lead to a greater risk of developing Cardiovascular Disease because it causes increased levels of triglycerides, which are fat-storing substances carried through the blood stream to the tissues. As your weight increases, stressors build up on the entire cardiovascular system. The heart and lungs, for example, have to work harder to distribute an adequate amount of freshly-oxygenated blood throughout the body. As well as the increase in triglycerides, there is also a lowering of “good” HDL cholesterol, which increases the risk of heart attack and stroke.

Increased insulin and glucose levels in those suffering from Metabolic Syndrome have also been proven to cause changes in the kidneys’ ability to remove salt, as well as increasing the risk of blood clot formation. All of these are key factors in the development of Cardiovascular Disease, heart attacks and stroke.

You may be interested in some of our Frequently Asked Questions (FAQs) about Metabolic Syndrome and the Insulite MetaX System.

Click here to read about the
Clinical Components of Metabolic Syndrome




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"I have been on the Insulite System for approx 3 months. I have lost 33 lbs, my liver functions are normal and my A1C came back at 5.1, down from 8.03 months ago. I was taking 10 Glucovance pills daily, now I take only 2 pills in the AM. My blood sugar is normal, my energy is higher than it has been in years and I feel great. Insulite along with a change in my diet has changed my life.

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  Santa Ana, CA
Insulin Resistance Articles
"In less than 3 weeks I've started losing weight again after being "stuck" on Weight Watchers for about a year. I've lost about 4 lbs since starting Insulite but more significantly my blood pressure is well within normal limits now and I can tell my metabolism is better. I am not getting that slump between meals and am able to control between-meal snacking, and I have a lot of energy throughout the day rather than periods where I need to nap. I just ordered the 6 months supply. Thank you!"
Teresa Ruth
  Boise, Idaho
"Researchers agree that insulin resistance is central to the metabolic syndrome. When target cells are unresponsive to insulin, the pancreas responds by pouring even more insulin into the bloodstream, leading to high levels of the hormone in the blood, a condition called compensatory hyperinsulinemia. The high level of insulin in the blood forces glucose into cells but also starts the events leading to arterial damage and eventually a heart attack. Under these conditions, a person may not manifest either diabetes or heart disease but could well be on the way to either or both."
A. MAUREEN ROUHI, Chemical and Engineering News. November 22, 2004.Vol. 82, No.47  
"I wanted to let you know how much I appreciate your caring advice and guiding me towards taking control of my health. It's hard to express in words how long I have been trying to find the answers you have so easily provided for me.

I am so excited about the positive changes in my health and I can't wait to see where I am six months from now, yet alone the year. Thank you again!"
MS
  Stuarts Draft, VA
"Simply losing 5-7% of your body fat (typically 10-15 pounds) and increasing your physical activity by taking a brisk walk 4-5 times a week can reduce your risk of developing Type II Diabetes by almost 60%."
Diabetes Prevention Program study 2001, study funded by the National Institute of Child Health and Human Development, et al.
"I started your product and found it really boosts my system, helping me get off ground zero, and stop the spiral downwards. It gave me the energy to start exercising and prepare healthy meals.

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"A non-pharmacologic treatment for these patients is needed, since drugs prescribed to lower blood pressure have been shown to actually worsen carbohydrate and lipid metabolism in Syndrome X patients, negating the beneficial effects of those drugs."
Duke University Study, results published in the Archives of Internal Medicine, September 2003.
Article by Dr. Sheri Colberg, Phd, FACSM
"I cannot believe the difference the Insulite System has made in how I feel. My appetite has changed tremendously. I do not crave carbs and sugar and my appetite is somewhat diminished."
PR
  Bakersfield, CA
"...approximately 90% of overweight Hispanic children with a family history for type 2 diabetes have at least one feature of the metabolic syndrome and 30% possess the metabolic syndrome.

Our results support the view that improving insulin resistance may be crucial in the prevention of both type 2 diabetes and premature cardiovascular disease in this at-risk subpopulation of Hispanic youth."
Cruz ML, Weigensberg MJ, Huang TT, Ball G, Shaibi GQ, Goran MI.,J Clin Endocrinol Metab. 2004 Jan;89(1):108-13.
"To gain the most benefit from modifying multiple metabolic risk factors, the underlying insulin-resistant state must become a target of therapy."
Bogdanovic, Streten and Langlans, Beata, "Metabolic Syndrome: New Opportunities in Diagnostics and Therapeutics", DMD Publications, 2004.  
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