Resistance-related Metabolic Syndrome, which can cause Cardiovascular Disease resulting in a heart attack or stroke, is
also being increasingly linked by researchers to numerous types
of cancer. These include breast, pancreatic and colon
cancer. Studies are also beginning to link excess abdominal fat
with a greater risk of some cancers.
Although the link is not yet clearly understood, scientists
believe that higher levels of glucose and insulin in the blood
stream – two of the hallmarks of Insulin Resistance and
Metabolic Syndrome – somehow stimulate cancer cell growth. In
women after menopause, excessive abdominal weight doubles the
risk of breast cancer regardless of overall weight.
Scientists believe that the components of Insulin Resistance and
Metabolic Syndrome – hyperinsulinemia, dyslipidemia, hypertension (high blood pressure) and atherosclerosis —
actually favor the growth of breast cancer cells, creating an
environment ripe for the development of this disease.
Researchers at the University of Buffalo, New York, were among
the first to show that Insulin Resistance may significantly
increase the risk of death from colon cancer, particularly among
women (1). There is also strong evidence that women with PCOS (Polycystic Ovarian Syndrome) are at higher risk of developing
endometrial and ovarian cancer (2).
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You may be interested in some of our Frequently Asked
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(1) Risk Factors and Life Expectancy Project, University of
Buffalo, results presented at the annual meeting of the Society
for Epidemiological Research. - Paolo Muti MD, Jain Liu, Maurizio Trevisan MD, Alessandro Menotti,
University of Buffalo
(2) Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathy is associated with significant morbidity in women.Carmina E, Lobo RA.
J Clin Endocrinol Metab. 1999 Jun;84(6):1897-9.
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about Insulin Resistance,
Metabolic Syndrome and Serious Conditions